Evidence-based Treatment Approaches in Bipolar Depression: A Patient Spotlight

Evidence-based Treatment Approaches in Bipolar Depression: A Patient Spotlight
1.3 ANCC Contact Hours 1.25 AMA PRA Category 1 Credit(s)
Launch Date:
September 03, 2015
Expiration Date:
The accreditation for this activity has expired.

Primary Audience:

Registered nurses, nurse practitioners, physicians, physician assistants

Relevant Terms:

Bipolar depression, bipolar disorders

Evelyn Parrish, PhD, APRN-BC

Evelyn Parrish, PhD, APRN-BC
Eastern Kentucky University
Richmond, KY

Evelyn Parrish, PhD, APRN-BC, has been a registered nurse since 1987 and a psychiatric mental health nurse practitioner since 1997. She completed her MSN (1997) and PhD (2008) at the University of Kentucky and received a post master's Psychiatric Mental Health Family Nurse Practitioner certificate from Rush University in 2009. She has been a professor at Eastern Kentucky University since 2006, where her primary responsibilities include coordinating and teaching in the Psychiatric Mental Health Nurse Practitioner program. Prior to working at Eastern Kentucky University, she was the director of clinical services at a behavioral healthcare clinic in Lexington, Kentucky. Dr. Parrish also currently serves as the medical director of a behavioral healthcare clinic and maintains a part-time clinical practice. She is the past president (2013–2014) of the International Society of Psychiatric-Mental Health Nurses. Her research interests include patient satisfaction with care and clinical outcomes of care.

Terence A. Ketter, MD

Terence A. Ketter, MD
Professor of Psychiatry and Behavioral Sciences
Stanford University
Stanford, CA

Dr. Terence Ketter obtained his medical degree from the University of Toronto and had internship and residency training in psychiatry at the University of California at San Francisco. He had subsequent fellowship training in brain imaging and psychopharmacology research methods at the Biological Psychiatry Branch of the National Institute of Mental Health in Bethesda, Maryland. He is currently Professor of Psychiatry & Behavioral Sciences and Chief of the Bipolar Disorders Clinic at the Stanford University School of Medicine in Stanford, California. Dr. Ketter's research interests include the use of brain imaging methods such as positron emission tomography (PET), magnetic resonance imaging (MRI), and magnetic resonance spectroscopy (MRS) to better understand the neurobiology of mood disorders and to explore the possibility of using these techniques to more effectively target treatments for patients with bipolar disorders. Dr. Ketter also conducts research in the use of novel medications and combinations of medications in the treatment of bipolar disorders, with an emphasis on the use of anticonvulsants.

In constant demand as a speaker, he presents at numerous national and international conferences and advisory boards, and sits on the review panel of several major scientific journals. Within the University, he serves on the Institutional Review Board, the body responsible for reviewing all new research proposals for scientific soundness, ethical conduct, and protection of human subjects.

Inspired by his clinical work with exceptionally creative individuals, Dr. Ketter has developed a strong interest in the relationship of creativity and mood disorders. In addition to his regular medical school and residency teaching duties, he is currently teaching a Sophomore Seminar course on Mood, Temperament, and Creativity. He is a featured panelist on the Alumni Association's Think Again tour.
1. Integrate mechanisms for distinguishing unipolar and bipolar depression into the diagnosis of patients who present with depressive symptoms
2. Proactively assess for and manage risk factors for suicidality
3. Incorporate evidence-based acute and maintenance treatments for bipolar depression, taking into account data that support their use, efficacy, and safety
4. Provide appropriate care and counsel for patients and their families

Accreditation Statement
This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Postgraduate Institute for Medicine and RMEI, LLC. The Postgraduate Institute for Medicine is accredited by the ACCME to provide continuing medical education for physicians.
Credit Designation
The Postgraduate Institute for Medicine designates this enduring material for a maximum of 1.25 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Credit Designation
This educational activity for 1.3 contact hours is provided by Postgraduate Institute for Medicine. Designated for 0.40 contact hours of pharmacotherapy credit for Advanced Practice Registered Nurses.
Accreditation Statement
Postgraduate Institute for Medicine is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center’s Commission on Accreditation. 
Postgraduate Institute for Medicine (PIM) requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose any real or apparent conflicts of interest (COI) they may have as related to the content of this activity. All identified COI are thoroughly vetted and resolved according to PIM policy. PIM is committed to providing its learners with high-quality CME activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of a commercial interest.
The faculty reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CME activity:
  • Evelyn Parrish, PhD, APRN-BC, has no affiliations with commercial interests to disclose.
  • Terence A. Ketter, MDhas affiliations with Sunovion Pharmaceuticals (Research Support); Teva Pharmaceuticals (Consultant); Janssen Pharmaceutica (Spouse Employment and Stock Holder); GlaxoSmithKline, Pfizer, Sunovion Pharmaceuticals (Speakers’ Bureau); Myriad Genetics, Inc., Merck, Sunovion Pharmaceuticals, Janssen Pharmaceutica (Advisory).
  • Jacqui Brooks, MBBCh, MRCPsych, has no affiliations with commercial interests to disclose.
  • Amy Reeve, has no affiliations with commercial interests to disclose.
Postgraduate Institute for Medicine
The following PIM planners and managers, Judi Smelker-Mitchek, RN, BSN, Trace Hutchison, PharmD, Samantha Mattiucci, PharmD, CCMEP, and Jan Schultz, MSN, RN, CCMEP, hereby state that they or their spouse/life partner do not have any financial relationships or relationships to products or devices with any commercial interest related to the content of this activity of any amount during the past 12 months.
Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patients' conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer's product information, and comparison with recommendations of other authorities.
This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications. 
The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.
Estimated time to complete: 1.25 hours
Medium: Internet

There is no fee for this educational activity.

This activity is supported by an independent educational grant from Sunovion.

By reviewing the course content and successfully completing the post-test and evaluation, registered nurses, nurse practitioners, physicians, and physician assistants are entitled to receive up to 1.25 AMA PRA Category 1 Credit(s)™ and 1.3 ANCC contact hours (0.40 pharmacotherapy contact hours). A statement of credit will be available to print from your user history page. Users must:
  • Read the learning objectives and faculty disclosures.
  • Participate in the activity.
  • Complete the post-test and activity evaluation.
Registered nurses, nurse practitioners, physicians, and physician assistants who successfully complete the post-test and evaluation will receive CME/CE credit. You must score 70% or higher on the post-test to receive credit for this activity. All other participants who successfully complete the post-test and evaluation will receive a certificate of participation.
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